Chain Reaction with Phemex CEO Federico Variola

Cointelegraph’s Ciaran Lyons sits down with Phemex CEO Federico Variola to discuss this week’s US CLARITY Act vote and why humans will always have a role in crypto trading, even as AI agents become more capable of handling trades.

26mSep 15, 2026

Chain Reaction: More episodes

Chain Reaction with Coin Bureau's Nic Puckrin
Cointelegraph’s Ciaran Lyons sits down with Coin Bureau founder Nic Puckrin to discuss how the crypto industry might look today if Donald Trump had never been elected president, and whether the industry would be in a better or worse position under an alternative administration.
28mSep 23, 2026
Chain Reaction with Himanshu Sahay
Cointelegraph's Ciaran Lyons speaks with Arch Lending co-founder Himanshu Sahay about which tokens are drawing the most interest in crypto lending, and how lending firms have strengthened their risk safeguards in the years since Celsius collapsed.
25mSep 23, 2026
Chain Reaction with Solstice CEO Ben Nadareski
Cointelegraph's Ciaran Lyons sits down with Solstice CEO Ben Nadareski to discuss why Solana's reputation as the memecoin capital of crypto may not be a bad thing, why he is bullish on the broader Solana ecosystem and his case for SOL reaching $1,000 by 2030.
26mSep 21, 2026
Chain Reaction with CoinShares' Luke Nolan
Cointelegraph's Ciaran Lyons sits down with CoinShares crypto researcher Luke Nolan to discuss the impact of the US Federal Reserve's recent interest rate increase on crypto markets, Germany's surprising progress in crypto adoption and why the UK appears to be falling behind.
27mSep 17, 2026
Chain Reaction with The Daily Wolf's Scott Melker
Cointelegraph’s Ciaran Lyons sits down with Scott Melker to discuss the US CLARITY Act stalling this week, what a potential interest rate hike could mean for crypto, and the crypto narratives Melker is most excited about heading into 2026.
28mSep 16, 2026
Chain Reaction US CLARITY Act bonus episode with 1inch and Fireblocks
Cointelegraph’s Ciaran Lyons sits down with 1inch Chief Legal Officer Orest Gavryliak and Fireblocks US Policy Director Jessica Martinez for a special episode of CHAIN REACTION to discuss the US CLARITY Act ahead of today’s vote, where the bill needs 60 votes to progress.
27mSep 15, 2026

Chain Reaction

Chain Reaction is a leading podcast that dives deep into the world of crypto, blockchain, and emerging technologies. Each episode features conversations with top founders, developers, and industry thinkers, breaking down the biggest trends, innovations, and ideas shaping the future of Web3.

Chain Reaction: More episodes

Chain Reaction with Coin Bureau's Nic Puckrin

Chain Reaction with Himanshu Sahay

Chain Reaction with Solstice CEO Ben Nadareski

Chain Reaction with CoinShares' Luke Nolan

Chain Reaction with The Daily Wolf's Scott Melker

Chain Reaction US CLARITY Act bonus episode with 1inch and Fireblocks

Chain Reaction